Clinical features of hypertrophic cardiomyopathy depending on the hereditary factor

The objective was to study the clinical features of symptomatic hypertrophic cardiomyopathy (HCM) depending on form (familial / non-familial), age onset and presence arterial hypertension (AH). Methods materials . During 6 years, we examined 250 HCM patients, 100 patients with aged from 18 86 years were included in study. Results Patients manifestations at a young more often had familial disease, an autosomal dominant type inheritance, asymmetric reverse curve interventricular septal morphology. On contrary, ≥45 non-familial disease basal hypertrophy. associated AH obese, CHF III–IV functional class (NYHA), larger anteroposterior left atrial diameter than without needed reduction. significantly angina syndrome. Absolute indications for reduction determined only AH. At same time, 50 % HCM+AH both older group, obesity. Conclusions morphology differs onset. Co-existing obesity are predictors progressive course increase proportion absolute reductions regardless